Research scientists from Schering-Plough Research Institute developed a rapid high-performance liquid chromatography (HPLC) technique that allows for efficient separation and analysis of pharmaceutical compounds.

The method uses a short column packed with 2.7μm “fused-core” silica particles that are made by fusing a 0.5μm layer of porous silica onto a solid …

“HPLC for Pharmaceutical Scientists” is a new hardcover book edited by Yuri V. Kazakevich and Rosario LoBrutto with a price tag of $159 at Amazon.

This is an excellent book for both novice and experienced pharmaceutical …

How many of you out there picked or even ate fresh bilberries? Probably not too many, unless you are from Northern Europe, Russia, or the Rocky Mountains of the US. The rest of us find bilberries in the form …

Here is another example of forensic application of HPLC that allows to classify and date the black gel pen ink entries on documents.

Gel pens first came out in 1984 in Japan and quickly became popular throughout the world due to their solid line, bold colors, and low cost. …

The HPLC method used a C8 column and the potassium chloride in aqueous acetic acid as a mobile phase with a linear gradient. The retention time was a bit over 20 min and the identity of the peak was confirmed as furosine by MS (mass spectrometry).

During the heating process carbonyl groups of sugars react with amino groups of amino acids and peptides forming a variety of products. The products of this, so-called, Maillard reaction contribute to flavor, aroma, and color of soy milk.

Nano HPLC is a relatively new development in chromatography world driven by recent advancements in proteomics that would require decreasing of inner diameter (ID) of liquid chromatography (LC) column to allow for a smaller sample amount and to increase sensitivity.

Scientist at Weber State University developed methods for extraction, identification and quantitation of xanthones and their derivatives: alpha-mangostin, 8-desoxygartanin, gartanin, beta-mangostin, 3-mangostin, and 9-hydroxycalabaxanthone.

Scientists from University of Hertfordshire (UK) are using new chemistry laboratories to analyze a random selection of red wines to determine the levels of resveratrol which is a natural antioxidant found in red wine and red grape skins