http://www.justchromatography.com Everything about Chromatography and Analytical Chemistry Tue, 09 Oct 2007 15:39:21 +0000 http://backend.userland.com/rss092 en These days gas chromatography (GC) is one of the primary analytical techniques used in every forensic laboratory. GC is widely used by forensic scientists - from analysis of body fluids for the presence of illegal substances, to testing of fiber and blood from a crime scene, and to detect residue ... http://www.justchromatography.com/gc/forensic-gc Scientists have measured heat conduction through a monolayer of hydrocarbon chains using a novel technique. Researchers understand heat transfer on the scales of individual molecules and in solids, but there is still much to learn about the physics of heat transfer in just a few molecules that will be used ... http://www.justchromatography.com/general/heat-flow-hydrocarbon In theory, the analyte sensitivity increases on decreasing the column inner diameter; however, because of the very low sample volumes injected - 20-60 nL, nano liquid chromatography cannot be considered as an analytical method of high sensitivity. There are several research studies that focused on the improvement of sensitivity by using ... http://www.justchromatography.com/nano-hplc/nano-lc-sensitivity Research scientists from Schering-Plough Research Institute developed a rapid high-performance liquid chromatography (HPLC) technique that allows for efficient separation and analysis of pharmaceutical compounds. The method uses a short column packed with 2.7μm "fused-core" silica particles that are made by fusing a 0.5μm layer of porous silica onto a solid silica ... http://www.justchromatography.com/hplc/hplc-fused-core Folks from India extracted 99.6% pure eicosapentaenoic acid (EPA) using silver ion (argentation) column chromatography from hydrolyzed sardine oil[1]. EPA and DHA (docosahexaenoic acid) are the two main long-chain polyunsaturated fatty acids, also frequently referred to as "omega-3". These lipids are primarily found in oily fish and shellfish. Some researches theorized ... http://www.justchromatography.com/column/fishy-chromatography Choosing the right column is key in Gas Chromatography. "Columns for Gas Chromatography: Performance and Selection" is a new hands-on reference for scientists and technicians working with packed column and capillary column gas chromatography. The authors Eugene F. Barry (University of Massachusetts Lowell) and Robert L. Grob (Villanova University) discuss the ... http://www.justchromatography.com/gc/columns-for-gc The biological cell is basically a miniature factory, which contains a large collection of dedicated protein machines. In a Review, Martin van den Heuvel and Cees Dekker look at recent progress in using some of these proteins to move, manipulate or power artificial, nanoscale devices. http://www.justchromatography.com/nanotech/motor-proteins I am continuing the series dedicated to the chromatography’s founder Mikhail Tsvet. So, in 1897 he moves to Russia from Switzerland, and here is his first impression of Russia: "...during the first six months that I have been in Russia, in vain, I have been trying to force myself to feel ... http://www.justchromatography.com/history/the-little-botanists Today I studied my blog's statistics to see what keywords people use to search in Google and Yahoo! to get to the pages of my site. Here is what I found based on the last 60 days of statistics: People used 1966 various search terms The top 20 keywords are: [TABLE=5] Then I looked at ... http://www.justchromatography.com/general/unanswered-questions Researchers have developed a new method for producing tandem solar cells, in which two solar cells working together to use a wider range of the solar spectrum. The physical properties of the semiconductor materials in each cell allow one to absorb light at longer wavelengths and the other to absorb light ... http://www.justchromatography.com/general/polymer-solar-cells Thank God for Greg's post "Odeur d'Asperge" over at Carbon Tet! The mystery is solved, and I thought my kidneys were failing and I would have to spend the rest of my life on dialysis. This spring I had become an avid admirer of the young asparagus shoots. And practically everyday ... http://www.justchromatography.com/gc/asparagusic-acid Scientists from Georgian Institute of Technology created a prototype nanogenerator that can generate electricity inside a human body. Tiny little devices traveling in our bloodstream while performing complete blood analysis and monitoring our well-being is the future of implantable biosensors. However, these nanorobots will need to be self-powered and there ... http://www.justchromatography.com/general/nanogenerators New research examines a class of reactions between neutral free radicals and neutral molecules that, unlike most reactions, happen rapidly at very low temperatures. Chemical reactions generally accelerate when temperature increase. However, in today's issue of Science Magazine [1] a research group from France revealed a class of gas-phase reaction between ... http://www.justchromatography.com/organic-chemistry/high-reactivity Cocaine is presently the most abused substance in Americas; however, the stimulant is gaining new advocates at an alarming rate in western Europe as well. In 2005, a group of researches from Italy analyzed water samples from the Po River in northern Italy for the presence of cocaine and its main ... http://www.justchromatography.com/gc/cocaine-pollution As I mentioned in the last post from this series, capillary columns of 10–100 μm inner diameter are commonly used in nano-liquid chromatography setups. They are typically made either from fused silica or PEEK materials currently found in your everyday Gas Chromatography or HPLC, respectively. There are three basic types of ... http://www.justchromatography.com/nano-hplc/columns-in-nano-lc As our planet is running out of petroleum resources, a new energy source must be found. Hydrogen is regarded as an ideal alternative to fossil fuel because of its abundance in environment, renewability, and zero emission. However, the most challenging and important aspect for the successful transition to a ... http://www.justchromatography.com/general/carbon-nanoscrolls-h2 Has anyone seen today's issue of Science? There is a research paper by Shannon Yan and colleagues "Do Vibrational Excitations of CHD3 Preferentially Promote Reactivity Toward the Chlorine Atom?" I had a difficult time following the authors - physical-molecular chemistry is not my strongest field, but nevertheless ... The study shows ... http://www.justchromatography.com/organic-chemistry/translational-vibrational "What is the response factor in chromatography?" is a question on Yahoo Answers. So far there has been two answers: 1) A wordy and a bit confusing text book reply tailored more towards Gas Chromatography. Response Factor The size of a spectral peak is proportional to the amount of the substance that reaches ... http://www.justchromatography.com/yahoo-answers/response-factor "HPLC for Pharmaceutical Scientists" is a new hardcover book edited by Yuri V. Kazakevich and Rosario LoBrutto with a price tag of $159 at Amazon. This is an excellent book for both novice and experienced pharmaceutical chemists that provides a unified approach to HPLC with a balanced treatment of the ... http://www.justchromatography.com/hplc/hplc-for-pharmaceutical-scientists ...well, the prescription ones at least. With Chinese manufacturers considering to increase exports of drug ingredients and perhaps even begin shipping finished drug products to the United States, an article "Trusting medicine from China: Close FDA scrutiny of Chinese pharmaceutical ingredients extends only to those for prescription drugs" in ... http://www.justchromatography.com/general/trusting-chinese-meds It is interesting to note that 20 years later there is still no clear definition of nano-LC. Due to a relatively large size of the columns used in nano-HPLC (10-140 μm), the method does not fall within the realm of the conventional definition of nanotechnology - "the control of matter ... http://www.justchromatography.com/nano-hplc/nano-lc-definition Thanks to one of the readers of this blog - Farooq, I now have the full text of an excellent, 21-page review by the researches from Rome and Spain entitled "Recent applications in nanoliquid chromatography" (DOI 10.1002/jssc.200700061). Two months ago, I did a small article about nano liquid chromatography to answer ... http://www.justchromatography.com/nano-hplc/nano-lc-intro This is the next post from the series dedicated to 135th birthday anniversary of Prof. Tsvet, the chromatography's founder. Today, the application of the principle of a chromatographic substance separation is the foundation of many breakthroughs in science and technology. The analysis of the amino acid and nucleotide sequence in proteins ... http://www.justchromatography.com/history/switzerland-russia New research on sulfate-reducing bacteria may offer good news for bioremediation efforts to clean up acid mine drainages and other environments with high levels of harmful metals. Sulfate-reducing bacteria is known to extract metal dissolved in anoxic waters and by isolating it into nanoscale particles. But, the tiny size ... http://www.justchromatography.com/biochemistry/toxic-waste-eating-bacteria A chromium catalyst is the key to efficiently converting glucose to a chemical feedstock with potential to replace many uses of crude oil including pharmaceuticals, cosmetics and plastics, scientists from Pacific Northwest National Laboratory report. As the world tries to emancipate itself from its oil addiction, researchers are seeking a ... http://www.justchromatography.com/general/plastic-that-grows A simple, cheap treatment using just oxygen could allow organic produce growers to store their crops for longer and go a long way towards reducing the price of organic fruit and vegetables. I admit that I am into organic produce but mostly because it tastes better and fresher than the conventionally ... http://www.justchromatography.com/biochemistry/organic-oxygen Today, it has been 3 years since I recovered from Rocky Mountain Spotted Fever or RMSF - a disease caused by Rickettsia rickettsii, a species of bacteria that is spread by hard ticks. On one hand, it is kind of cool that I had contracted a relatively rare and ... http://www.justchromatography.com/biochemistry/rocky-mountain-spotted-fever