Comments on: Cocaine Pollution http://www.justchromatography.com/gc/cocaine-pollution Everything about Chromatography and Analytical Chemistry Fri, 16 May 2008 03:27:22 +0000 http://wordpress.org/?v=2.3 By: Mitch http://www.justchromatography.com/gc/cocaine-pollution#comment-310 Mitch Mon, 16 Jul 2007 08:20:40 +0000 http://www.justchromatography.com/gc/cocaine-pollution#comment-310 Mass specs will of course have peaks for benzoylecgonine. But fragmentation patterns matter, plus how far above the sample to blank i.e. "noise" ratio becomes important. Mass specs will of course have peaks for benzoylecgonine. But fragmentation patterns matter, plus how far above the sample to blank i.e. “noise” ratio becomes important.

]]> By: Chemist http://www.justchromatography.com/gc/cocaine-pollution#comment-297 Chemist Thu, 12 Jul 2007 18:49:50 +0000 http://www.justchromatography.com/gc/cocaine-pollution#comment-297 Kiwi, You have a valid concern; however, I do tend to trust the researchers. You can read the entire report here - http://www.ehjournal.net/content/4/1/14 They had no cocaine in any of their blanks, so I would rule out contamination. "Instrumental blanks (standard solution with IS only), showed no traces of interfering compounds. Procedural blanks and recoveries were performed using mineral water. Blanks showed no detectable cocaine and BE [benzoylecgonine] . Recoveries were >90% for both compounds" Kiwi,

You have a valid concern; however, I do tend to trust the researchers. You can read the entire report here - http://www.ehjournal.net/content/4/1/14

They had no cocaine in any of their blanks, so I would rule out contamination.

“Instrumental blanks (standard solution with IS only), showed no traces of interfering compounds. Procedural blanks and recoveries were performed using mineral water. Blanks showed no detectable cocaine and BE [benzoylecgonine] . Recoveries were >90% for both compounds”

]]> By: kyle keeton http://www.justchromatography.com/gc/cocaine-pollution#comment-295 kyle keeton Thu, 12 Jul 2007 09:14:11 +0000 http://www.justchromatography.com/gc/cocaine-pollution#comment-295 The labs are a controlled environment. That should have filtered air. The stored cocaine is under controls. I believe that it is possible. This problem is in America the same way. Kyle The labs are a controlled environment. That should have filtered air. The stored cocaine is under controls. I believe that it is possible. This problem is in America the same way.

Kyle

]]> By: kiwi http://www.justchromatography.com/gc/cocaine-pollution#comment-292 kiwi Wed, 11 Jul 2007 11:40:34 +0000 http://www.justchromatography.com/gc/cocaine-pollution#comment-292 ok, query from a non-analytical chemist - presumably these labs all have cocaine and its metabolites somewhere in the lab, as authentic standards. so whats to stop the pg of cocaciane dust floating around the lab from contaminating their samples, leading to their results? they seem to find cocaine wherever they look for it - and quite a lot of cocaine too. It makes more sense to me than 40 000 doses of cocaine/day floating down the river ok, query from a non-analytical chemist - presumably these labs all have cocaine and its metabolites somewhere in the lab, as authentic standards. so whats to stop the pg of cocaciane dust floating around the lab from contaminating their samples, leading to their results? they seem to find cocaine wherever they look for it - and quite a lot of cocaine too. It makes more sense to me than 40 000 doses of cocaine/day floating down the river

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