Chromatography

Tags: HPLC UHPLC

Research scientists from Schering-Plough Research Institute developed a rapid high-performance liquid chromatography (HPLC) technique that allows for efficient separation and analysis of pharmaceutical compounds.
The method uses a short column packed with 2.7μm “fused-core” silica particles that are made by fusing a 0.5μm layer of porous silica onto a solid silica particle[1]. These unique particles […]

Tags: CZE HPLC soy statistics

Today I studied my blog’s statistics to see what keywords people use to search in Google and Yahoo! to get to the pages of my site.
Here is what I found based on the last 60 days of statistics:

People used 1966 various search terms
The top 20 keywords are:

Top 20

Term
Perc

chromatography
20.04%

witricity
3.76%

response factor
3.15%

wireless power transfer via strongly coupled magnetic […]

Tags: capillary HPLC liquid_chromatography monolithic nanoliquid

Nano Liquid ChromatographyNano Liquid Chromatography - ReloadedDefinition of Nano Liquid ChromatographyColumns in Nano LCNano LC Sensitivity As I mentioned in the last post from this series, capillary columns of 10–100 μm inner diameter are commonly used in nano-liquid chromatography setups. They are typically made either from fused silica or PEEK materials currently found in your […]

Tags: chromatographic chromatography Gas Chromatography HPLC LCMS Mass Spectrometry

“HPLC for Pharmaceutical Scientists” is a new hardcover book edited by Yuri V. Kazakevich and Rosario LoBrutto with a price tag of $159 at Amazon.
This is an excellent book for both novice and experienced pharmaceutical chemists that provides a unified approach to HPLC with a balanced treatment of the theory and practice of HPLC […]

Tags: amaranth anthocyanin bilberry HPLC NMR

How many of you out there picked or even ate fresh bilberries? Probably not too many, unless you are from Northern Europe, Russia, or the Rocky Mountains of the US. The rest of us find bilberries in the form of purple capsules in dietary supplements.
Bilberry is small shrub to a one foot in […]

Tags: HPLC lab-on-a-chip LCMS nanotechnology

Almost two weeks ago there was a question regarding Nano HPLC technology that I attempted to answer and in that post I mentioned Agilent as one of the pioneers in the Nano LC field. Agilent’s “nano” workhorse is a 1200 Series HPLC-Chip/MS system, which uses microfluidics chip-based technology for nanospray LC/MS. Based on […]

Tags: Gas Chromatography HPLC IC Mass Spectrometry

This is another Q&A from Yahoo! Answers which I could not stay away from. The question was asked by “pigpigletpoker” and has already received two answers.
Dave_Stark said:
Make a chromatogram of the paint found on the other car involved in the accident.
Then do a side-by-side chromatogram of the red paint from the two suspect cars. […]

Tags: chromatography forensic HPLC

Here is another example of forensic application of HPLC that allows to classify and date the black gel pen ink entries on documents.
Gel pens first came out in 1984 in Japan and quickly became popular throughout the world due to their solid line, bold colors, and low cost. They are also regarded as environmentally […]

Tags: CZE furosine HPLC isoflavones Nano HPLC protein

The HPLC method used a C8 column and the potassium chloride in aqueous acetic acid as a mobile phase with a linear gradient. The retention time was a bit over 20 min and the identity of the peak was confirmed as furosine by MS (mass spectrometry).

Tags: carbonyl_groups CZE electrophoresis furosine HPLC isoflavones lysine maillard protein soy soybeans

During the heating process carbonyl groups of sugars react with amino groups of amino acids and peptides forming a variety of products. The products of this, so-called, Maillard reaction contribute to flavor, aroma, and color of soy milk.