Handbook of HPLC, Second Edition (Chromatographic Science Series)Several months ago a second edition of  “Handbook of HPLC” was released. The new edition avoids well-established theoretical and practical aspects of HPLC that were extensively covered in the first edition published in 1998. However, the editors greatly update the handbook with emerging novel methods and concepts  that have contributed to the further advancement of HPLC technique in the last 12 years. Here are some examples of these new aspects:

  • Chapter 1  – monolithic columns (monolithic materials, pore formation,  near-IR,  chromatographic application)
  • Chapter 3 – micro-HPLC (μHPLC systems, micro-columns, gradient elution)
  • Chapter 4 – two-dimensional comprehensive LC
  • Chapter 5 – gradient elution mode
  • Chapter 6 – capillary electromigration techniques
  • Chapter 8 – LC-MS Interfaces
  • Chpater 16 – Polymer HPLC

Part II focuses on the four major practical applications of HPLC analysis:

  • Chiral Pharmaceutical (method development using CSP and CMPA)
  • Environmental
  • Food
  • Forensic Sciences (toxicology, explosives, dyes and ink, DNA analysis)

All chapters include extensive reference lists and summarizing tables.

Danilo Corradini (editor) and Terry M. Phillips (consulting editor) assert that “this edition is suitable as a textbook for undergraduate college students having a general background in chromatography and for new practitioners interested in improving their knowledge on the current status and future trends of HPLC“.

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