This occurs when voids are created in the packing material of a column. It results in the mobile phase and accompanying solutes moving more rapidly than the average flow velocity producing band broadening. These voids are created by poor packing or by erosion of the packed bed.

One Response to “Channeling”

  1. akshay says:

    how can we decide whether channeling is happening in column chromatography bed.any literature on that ??

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