Differential Refractive Index (RI)

Detectors that identify the difference in the mobile phaseĆ¢??s refractive index when it contains dissolved sample. RI detectors are universal detectors which respond to the presence of all compounds. Because the RI detector responds to changes in mobile phase composition, they are not suitable for gradient methods. RI detectors are less sensitive than UV/Vis detectors, but are useful when the sample molecule does not have a chromophore.

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